Cyclacel Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing cancer medicines based on cell cycle, transcriptional regulation and mitosis control biology. The transcriptional regulation program is evaluating fadraciclib, a Cyclin-dependent kinase 9 (CDK9) inhibitor, in solid tumors and hematological malignancies.
The epigenetic/anti-mitotic program is evaluating plogosertib, in solid tumors and hematological malignancies. The Company's Plogosertib is a novel, small molecule, selective and potent Polo-like kinase 1 (PLK1) inhibitor, which has demonstrated potent and selective target inhibition (PLK1 IC50 approximately 3 nM) and efficacy in human tumor xenografts at non-toxic doses.
Its translational biology program supports the development of plogosertib in solid tumor and hematological malignancy indications..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 53.8K |
Three Month Average Volume | 2.0M |
High Low | |
Fifty-Two Week High | 11.343 USD |
Fifty-Two Week Low | 0.9517 USD |
Fifty-Two Week High Date | 19 Oct 2023 |
Fifty-Two Week Low Date | 29 Aug 2024 |
Price and Volume | |
Current Price | 1.052 USD |
Beta | 1 |
Relative Price Change | |
Four Week Relative Price Change | -38.53% |
Thirteen Week Relative Price Change | -62.77% |
Twenty-Six Week Relative Price Change | -67.01% |
Fifty-Two Week Relative Price Change | -85.87% |
Year-to-Date Relative Price Change | -66.73% |
Price Change | |
One Day Price Change | 1.15% |
Thirteen Week Price Change | -60.15% |
Twenty-Six Week Price Change | -63.72% |
Five Day Price Change | -13.76% |
Fifty-Two Week Price Change | -82.29% |
Year-to-Date Price Change | -60.60% |
Month-to-Date Price Change | -35.85% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 0.57324 USD |
Book Value Per Share (Most Recent Quarter) | 0.5534 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 0.57324 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 0.5534 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -10.67882 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0.49364 USD |
Revenue Per Share (Trailing Twelve Months) | 0.04232 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0.15 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -26.74612 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -16.13773 USD |
Normalized (Last Fiscal Year) | -26.74612 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -26.74612 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -16.13773 USD |
Including Extraordinary Items (Last Fiscal Year) | -26.74612 USD |
Including Extraordinary Items (Trailing Twelve Months) | -16.13773 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 3.19013 USD |
Cash Per Share (Most Recent Quarter) | 3.32373 USD |
Cash Flow Per Share (Last Fiscal Year) | -26.70953 USD |
Cash Flow Per Share (Trailing Twelve Months) | -9.30436 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -6.14383 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -17,622 |
Cash Flow Revenue (Trailing Twelve Months) | -14,516 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -25,452.50% |
Pretax Margin (Last Fiscal Year) | -6,083.57% |
Pretax Margin (5 Year) | -22,144.52% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -6,060.24% |
Operating Margin (Trailing Twelve Months) | -25,255.00% |
Operating Margin (5 Year) | -22,944.05% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -5,370.24% |
Net Profit Margin (Trailing Twelve Months) | -21,882.50% |
Net Profit Margin (5 Year) | -18,789.29% |
Growth | |
---|---|
Book Value | |
Book Value Per Share (5 Year) | -72.53% |
Tangible Book Value (5 Year) | -47.54% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -98.93% |
Revenue Growth (3 Year) | 22.87% |
Revenue Change (Trailing Twelve Months) | -78.55% |
Revenue Per Share Growth | -33.23% |
Revenue Growth (5 Year) | -99,999.99% |
Capital Spending Debt | |
Capital Spending (5 Year) | -31.23% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | 89.04% |
EPS Change (Trailing Twelve Months) | 43.90% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
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Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 3 |
Price to Tangible Book (Most Recent Quarter) | 2 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -6,000,000 |
Net Debt (Last Fiscal Year) | -3,378,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | 5 |
Price to Sales (Trailing Twelve Months) | 26 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 14.26% |
Price to Book | |
Price to Book (Last Fiscal Year) | 2 |
Price to Book (Most Recent Quarter) | 2 |
Financial Strength | |
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Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 0 |
Long Term Debt to Equity (Most Recent Quarter) | 0 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 1 |
Current Ratio (Most Recent Quarter) | 1 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -16,319,000 |
Free Cash Flow (Trailing Twelve Months) | -11,613,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -172 |
Net Interest Coverage (Trailing Twelve Months) | -101 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 0 |
Total Debt to Equity (Most Recent Quarter) | 0 |
Management Effectiveness | |
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Return on Assets | |
Return on Assets (Last Fiscal Year) | -122.40% |
Return on Assets (Trailing Twelve Months) | -142.14% |
Return on Assets (5 Year) | -57.58% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -216.31% |
Return on Equity (Trailing Twelve Months) | -331.28% |
Return on Equity (5 Year) | -75.68% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -212.95% |
Return on Investment (Trailing Twelve Months) | -327.21% |
Return on Investment (5 Year) | -69.81% |