MAIA Biotechnology, Inc. is a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer. The Company's THIO (6-thio-dG, 6-thio-2'-deoxyguanosine) is a first-in-class investigational telomere-targeting agent in clinical development to evaluate its activity in Non-Small Cell Lung Cancer (NSCLC).
The modified nucleotide 6-thio-2-deoxyguanosine (THIO) induces telomerase-dependent telomeric DNA modification, DNA damage responses, and selective cancer cell death. THIO-damaged telomeric fragments accumulate in cytosolic micronuclei and activates both innate (cGAS/STING) and adaptive (T-cell) immune responses.
The sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in tumor regression in advanced, in vivo cancer models by induction of cancer type-specific immune memory. THIO is being developed as a second or later line of treatment for NSCLC for patients that have progressed beyond the standard-of-care regimen of existing checkpoint inhibitors..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 63.6K |
Three Month Average Volume | 5.1M |
High Low | |
Fifty-Two Week High | 5.99 USD |
Fifty-Two Week Low | 0.82 USD |
Fifty-Two Week High Date | 03 Jun 2024 |
Fifty-Two Week Low Date | 11 Dec 2023 |
Price and Volume | |
Current Price | 3.04 USD |
Beta | -100,000 |
Relative Price Change | |
Four Week Relative Price Change | -2.46% |
Thirteen Week Relative Price Change | -40.20% |
Twenty-Six Week Relative Price Change | 98.19% |
Fifty-Two Week Relative Price Change | 38.63% |
Year-to-Date Relative Price Change | 119.41% |
Price Change | |
One Day Price Change | 8.57% |
Thirteen Week Price Change | -36.00% |
Twenty-Six Week Price Change | 117.92% |
Five Day Price Change | 2.01% |
Fifty-Two Week Price Change | 73.71% |
Year-to-Date Price Change | 159.83% |
Month-to-Date Price Change | -5.88% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 0.02811 USD |
Book Value Per Share (Most Recent Quarter) | 0.1332 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 0.02811 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 0.1332 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -1.1077 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0 USD |
Revenue Per Share (Trailing Twelve Months) | 0 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -1.49099 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -1.61888 USD |
Normalized (Last Fiscal Year) | -1.49099 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -1.49099 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -1.61888 USD |
Including Extraordinary Items (Last Fiscal Year) | -1.49099 USD |
Including Extraordinary Items (Trailing Twelve Months) | -1.61888 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 0.42097 USD |
Cash Per Share (Most Recent Quarter) | 0.4878 USD |
Cash Flow Per Share (Last Fiscal Year) | -99999.99 USD |
Cash Flow Per Share (Trailing Twelve Months) | -99999.99 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -0.89447 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -100,000 |
Cash Flow Revenue (Trailing Twelve Months) | -100,000 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -99,999.99% |
Pretax Margin (Last Fiscal Year) | -99,999.99% |
Pretax Margin (5 Year) | -99,999.99% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -99,999.99% |
Operating Margin (Trailing Twelve Months) | -99,999.99% |
Operating Margin (5 Year) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -99,999.99% |
Net Profit Margin (Trailing Twelve Months) | -99,999.99% |
Net Profit Margin (5 Year) | -99,999.99% |
Growth | |
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Book Value | |
Book Value Per Share (5 Year) | -99,999.99% |
Tangible Book Value (5 Year) | -99,999.99% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -99,999.99% |
Revenue Growth (3 Year) | -99,999.99% |
Revenue Change (Trailing Twelve Months) | -99,999.99% |
Revenue Per Share Growth | -99,999.99% |
Revenue Growth (5 Year) | -99,999.99% |
Capital Spending Debt | |
Capital Spending (5 Year) | -99,999.99% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | -13.91% |
EPS Change (Trailing Twelve Months) | -2.04% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
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Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 152 |
Price to Tangible Book (Most Recent Quarter) | 23 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -11,579,390 |
Net Debt (Last Fiscal Year) | -7,150,700 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | -100,000 |
Price to Sales (Trailing Twelve Months) | -100,000 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 108 |
Price to Book (Most Recent Quarter) | 23 |
Financial Strength | |
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Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 0 |
Long Term Debt to Equity (Most Recent Quarter) | 0 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 2 |
Current Ratio (Most Recent Quarter) | 3 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -13,071,020 |
Free Cash Flow (Trailing Twelve Months) | -15,421,310 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -100,000 |
Net Interest Coverage (Trailing Twelve Months) | -100,000 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 0 |
Total Debt to Equity (Most Recent Quarter) | 0 |
Management Effectiveness | |
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Return on Assets | |
Return on Assets (Last Fiscal Year) | -201.88% |
Return on Assets (Trailing Twelve Months) | -251.96% |
Return on Assets (5 Year) | -99,999.99% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -440.12% |
Return on Equity (Trailing Twelve Months) | -559.56% |
Return on Equity (5 Year) | -99,999.99% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -347.42% |
Return on Investment (Trailing Twelve Months) | -362.21% |
Return on Investment (5 Year) | -99,999.99% |