Prelude Therapeutics Incorporated is a clinical-stage fully integrated oncology company built on a foundation of drug discovery to deliver novel precision cancer medicines to underserved patients. It has developed a diverse pipeline consisting of multiple distinct programs: kinases, targeted protein degraders, and precision antibody drug conjugates.
Its product candidates include PRT3789, PRT2527 and PRT3645. PRT3789 is a highly selective degrader of SMARCA2 protein, which along with SMARCA4, controls gene regulation through chromatin remodeling. Its CDK9 program is an essential regulator of cancer-promoting transcriptional programs, including those driven by MCL1, MYC and MYB.
PRT3645 is a brain and tissue penetrant molecule that potently targets CDK4/6 with a biased selectivity for CDK4. PRT2527 is designed to be a potent and selective CDK9 inhibitor. Its MCL1 candidate, PRT1419, is designed to be a potent and selective inhibitor of the anti-apoptotic protein, MCL1..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 248.7K |
Three Month Average Volume | 3.0M |
High Low | |
Fifty-Two Week High | 6.8 USD |
Fifty-Two Week Low | 1.66 USD |
Fifty-Two Week High Date | 14 Aug 2024 |
Fifty-Two Week Low Date | 01 Nov 2023 |
Price and Volume | |
Current Price | 5.2 USD |
Beta | 2 |
Relative Price Change | |
Four Week Relative Price Change | -15.72% |
Thirteen Week Relative Price Change | 26.20% |
Twenty-Six Week Relative Price Change | 3.03% |
Fifty-Two Week Relative Price Change | 11.26% |
Year-to-Date Relative Price Change | 2.84% |
Price Change | |
One Day Price Change | 0.00% |
Thirteen Week Price Change | 35.06% |
Twenty-Six Week Price Change | 13.29% |
Five Day Price Change | -3.17% |
Fifty-Two Week Price Change | 39.41% |
Year-to-Date Price Change | 21.78% |
Month-to-Date Price Change | -18.37% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 5.63641 USD |
Book Value Per Share (Most Recent Quarter) | 4.32362 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 5.63641 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 4.32362 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -1.95038 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0 USD |
Revenue Per Share (Trailing Twelve Months) | 0 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -2.01852 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -1.80133 USD |
Normalized (Last Fiscal Year) | -2.01852 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -2.01852 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -1.80133 USD |
Including Extraordinary Items (Last Fiscal Year) | -2.01852 USD |
Including Extraordinary Items (Trailing Twelve Months) | -1.80133 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 5.53763 USD |
Cash Per Share (Most Recent Quarter) | 4.26593 USD |
Cash Flow Per Share (Last Fiscal Year) | -1.99915 USD |
Cash Flow Per Share (Trailing Twelve Months) | -1.77835 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -1.47511 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -100,000 |
Cash Flow Revenue (Trailing Twelve Months) | -100,000 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -99,999.99% |
Pretax Margin (Last Fiscal Year) | -99,999.99% |
Pretax Margin (5 Year) | -99,999.99% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -99,999.99% |
Operating Margin (Trailing Twelve Months) | -99,999.99% |
Operating Margin (5 Year) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -99,999.99% |
Net Profit Margin (Trailing Twelve Months) | -99,999.99% |
Net Profit Margin (5 Year) | -99,999.99% |
Growth | |
---|---|
Book Value | |
Book Value Per Share (5 Year) | 11.60% |
Tangible Book Value (5 Year) | 76.35% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -99,999.99% |
Revenue Growth (3 Year) | -99,999.99% |
Revenue Change (Trailing Twelve Months) | -99,999.99% |
Revenue Per Share Growth | -99,999.99% |
Revenue Growth (5 Year) | -99,999.99% |
Capital Spending Debt | |
Capital Spending (5 Year) | 46.03% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | 15.26% |
EPS Change (Trailing Twelve Months) | 23.47% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
---|---|
Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 1 |
Price to Tangible Book (Most Recent Quarter) | 2 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -179,337,000 |
Net Debt (Last Fiscal Year) | -232,935,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | -100,000 |
Price to Sales (Trailing Twelve Months) | -100,000 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 1 |
Price to Book (Most Recent Quarter) | 1 |
Financial Strength | |
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Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 0 |
Long Term Debt to Equity (Most Recent Quarter) | 0 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 11 |
Current Ratio (Most Recent Quarter) | 8 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -110,576,000 |
Free Cash Flow (Trailing Twelve Months) | -106,477,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -100,000 |
Net Interest Coverage (Trailing Twelve Months) | -100,000 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 0 |
Total Debt to Equity (Most Recent Quarter) | 0 |
Management Effectiveness | |
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Return on Assets | |
Return on Assets (Last Fiscal Year) | -48.91% |
Return on Assets (Trailing Twelve Months) | -51.44% |
Return on Assets (5 Year) | -47.21% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -56.33% |
Return on Equity (Trailing Twelve Months) | -58.45% |
Return on Equity (5 Year) | -57.69% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -53.60% |
Return on Investment (Trailing Twelve Months) | -55.69% |
Return on Investment (5 Year) | -51.07% |