aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs.
Efzofitimod is a tRNA synthetase derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS).
ATYR0101 binds directly to latent-transforming growth factor beta-binding protein 1 (LTBP1), which regulates transforming growth factor beta (TGFb). Its ATYR0750 is a fusion protein derived from a domain of alanyl-tRNA synthetase (AARS)..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 208.3K |
Three Month Average Volume | 8.0M |
High Low | |
Fifty-Two Week High | 2.5 USD |
Fifty-Two Week Low | 1.0801 USD |
Fifty-Two Week High Date | 25 Jul 2024 |
Fifty-Two Week Low Date | 13 Nov 2023 |
Price and Volume | |
Current Price | 1.87 USD |
Beta | 1 |
Relative Price Change | |
Four Week Relative Price Change | -3.27% |
Thirteen Week Relative Price Change | 0.99% |
Twenty-Six Week Relative Price Change | -10.96% |
Fifty-Two Week Relative Price Change | -12.22% |
Year-to-Date Relative Price Change | 12.00% |
Price Change | |
One Day Price Change | -1.06% |
Thirteen Week Price Change | 8.09% |
Twenty-Six Week Price Change | -2.09% |
Five Day Price Change | -1.06% |
Fifty-Two Week Price Change | 10.00% |
Year-to-Date Price Change | 32.62% |
Month-to-Date Price Change | -5.56% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 1.4325 USD |
Book Value Per Share (Most Recent Quarter) | 1.07668 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 1.4325 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 1.07668 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -0.96753 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0.00659 USD |
Revenue Per Share (Trailing Twelve Months) | 0.0092 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -0.93998 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -0.90472 USD |
Normalized (Last Fiscal Year) | -0.93998 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -0.93998 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -0.90472 USD |
Including Extraordinary Items (Last Fiscal Year) | -0.93998 USD |
Including Extraordinary Items (Trailing Twelve Months) | -0.90472 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 1.55114 USD |
Cash Per Share (Most Recent Quarter) | 1.03543 USD |
Cash Flow Per Share (Last Fiscal Year) | -0.92894 USD |
Cash Flow Per Share (Trailing Twelve Months) | -0.89508 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -1.00243 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -693 |
Cash Flow Revenue (Trailing Twelve Months) | -10,893 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -9,846.26% |
Pretax Margin (Last Fiscal Year) | -14,276.77% |
Pretax Margin (5 Year) | -784.19% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -15,557.79% |
Operating Margin (Trailing Twelve Months) | -10,633.50% |
Operating Margin (5 Year) | -806.01% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -14,276.77% |
Net Profit Margin (Trailing Twelve Months) | -9,846.26% |
Net Profit Margin (5 Year) | -784.19% |
Growth | |
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Book Value | |
Book Value Per Share (5 Year) | -37.82% |
Tangible Book Value (5 Year) | 21.92% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -99,999.99% |
Revenue Growth (3 Year) | -99,999.99% |
Revenue Change (Trailing Twelve Months) | -94.34% |
Revenue Per Share Growth | -99,999.99% |
Revenue Growth (5 Year) | -67.68% |
Capital Spending Debt | |
Capital Spending (5 Year) | 47.98% |
Total Debt (5 Year) | -34.55% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | -0.82% |
EPS Change (Trailing Twelve Months) | 26.40% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
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Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 2 |
Price to Tangible Book (Most Recent Quarter) | 2 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -76,801,000 |
Net Debt (Last Fiscal Year) | -96,241,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | 402 |
Price to Sales (Trailing Twelve Months) | 241 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 1 |
Price to Book (Most Recent Quarter) | 2 |
Financial Strength | |
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Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 2 |
Long Term Debt to Equity (Most Recent Quarter) | 1 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 6 |
Current Ratio (Most Recent Quarter) | 8 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -37,436,000 |
Free Cash Flow (Trailing Twelve Months) | -64,049,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -100,000 |
Net Interest Coverage (Trailing Twelve Months) | -100,000 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 2 |
Total Debt to Equity (Most Recent Quarter) | 2 |
Management Effectiveness | |
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Return on Assets | |
Return on Assets (Last Fiscal Year) | -46.57% |
Return on Assets (Trailing Twelve Months) | -48.51% |
Return on Assets (5 Year) | -45.45% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -62.16% |
Return on Equity (Trailing Twelve Months) | -61.64% |
Return on Equity (5 Year) | -57.25% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -54.04% |
Return on Investment (Trailing Twelve Months) | -53.89% |
Return on Investment (5 Year) | -52.74% |