Carisma Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on utilizing its proprietary macrophage and monocyte cell engineering platform to develop transformative immunotherapies to treat cancer and other serious diseases. It is developing a pipeline of product candidates, with an initial focus on advancing multiple ex vivo autologous and in vivo CAR-M therapies for the treatment of solid tumors.
Its first product candidate, CT-0508, is an ex vivo gene-modified autologous chimeric antigen receptor-monocyte (CAR-Monocyte) cellular therapy intended to treat solid tumors that overexpress human epidermal growth factor receptor 2 (HER2). Its second product candidate, CT-0525, is an ex vivo gene-modified autologous chimeric antigen receptor-macrophage (CAR-Macrophage) cellular therapy intended to treat solid tumors that overexpress HER2.
CT-1119 is a mesothelin-targeted CAR-Monocyte that is designed to treat patients with advanced mesothelin-positive solid tumors..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 129.1K |
Three Month Average Volume | 17.0M |
High Low | |
Fifty-Two Week High | 6.975 USD |
Fifty-Two Week Low | 0.8 USD |
Fifty-Two Week High Date | 01 Sep 2023 |
Fifty-Two Week Low Date | 07 Aug 2024 |
Price and Volume | |
Current Price | 1.07 USD |
Beta | 2 |
Relative Price Change | |
Four Week Relative Price Change | 3.87% |
Thirteen Week Relative Price Change | -24.83% |
Twenty-Six Week Relative Price Change | -62.43% |
Fifty-Two Week Relative Price Change | -87.66% |
Year-to-Date Relative Price Change | -69.16% |
Price Change | |
One Day Price Change | -1.83% |
Thirteen Week Price Change | -19.55% |
Twenty-Six Week Price Change | -58.69% |
Five Day Price Change | -5.31% |
Fifty-Two Week Price Change | -84.54% |
Year-to-Date Price Change | -63.48% |
Month-to-Date Price Change | 0.00% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 0.65334 USD |
Book Value Per Share (Most Recent Quarter) | 0.00867 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 0.65334 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 0.00867 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -1.77925 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0.44502 USD |
Revenue Per Share (Trailing Twelve Months) | 0.50749 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -2.59153 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -1.78143 USD |
Normalized (Last Fiscal Year) | -2.59153 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -2.59153 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -1.78143 USD |
Including Extraordinary Items (Last Fiscal Year) | -2.59153 USD |
Including Extraordinary Items (Trailing Twelve Months) | -1.78143 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 1.91099 USD |
Cash Per Share (Most Recent Quarter) | 0.97153 USD |
Cash Flow Per Share (Last Fiscal Year) | -2.50691 USD |
Cash Flow Per Share (Trailing Twelve Months) | -1.69415 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -1.87494 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -210 |
Cash Flow Revenue (Trailing Twelve Months) | -369 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -351.03% |
Pretax Margin (Last Fiscal Year) | -582.34% |
Pretax Margin (5 Year) | -267.21% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -594.75% |
Operating Margin (Trailing Twelve Months) | -366.85% |
Operating Margin (5 Year) | -272.66% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -582.34% |
Net Profit Margin (Trailing Twelve Months) | -350.08% |
Net Profit Margin (5 Year) | -255.66% |
Growth | |
---|---|
Book Value | |
Book Value Per Share (5 Year) | -43.57% |
Tangible Book Value (5 Year) | -99,999.99% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | 158.34% |
Revenue Growth (3 Year) | -99,999.99% |
Revenue Change (Trailing Twelve Months) | -55.75% |
Revenue Per Share Growth | -99,999.99% |
Revenue Growth (5 Year) | 9.91% |
Capital Spending Debt | |
Capital Spending (5 Year) | 255.27% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | 45.58% |
EPS Change (Trailing Twelve Months) | -57.12% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
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Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 2 |
Price to Tangible Book (Most Recent Quarter) | 123 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -38,577,000 |
Net Debt (Last Fiscal Year) | -76,733,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | 3 |
Price to Sales (Trailing Twelve Months) | 2 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | 1 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | 1 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 2 |
Price to Book (Most Recent Quarter) | 123 |
Financial Strength | |
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Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 1 |
Long Term Debt to Equity (Most Recent Quarter) | 139 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 5 |
Current Ratio (Most Recent Quarter) | 3 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -82,309,000 |
Free Cash Flow (Trailing Twelve Months) | -76,514,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -100,000 |
Net Interest Coverage (Trailing Twelve Months) | -100,000 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 3 |
Total Debt to Equity (Most Recent Quarter) | 496 |
Management Effectiveness | |
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Return on Assets | |
Return on Assets (Last Fiscal Year) | -62.34% |
Return on Assets (Trailing Twelve Months) | -75.38% |
Return on Assets (5 Year) | -30.87% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -94.06% |
Return on Equity (Trailing Twelve Months) | -216.21% |
Return on Equity (5 Year) | -72.00% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -74.95% |
Return on Investment (Trailing Twelve Months) | -91.33% |
Return on Investment (5 Year) | -34.47% |