Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the discovery, development, and commercialization of targeted therapies for women's cancers. Its lead product candidate, OP-1250, is an oral therapy with combined activity as both a complete estrogen receptor (ER) antagonist (CERAN) and a selective ER degrader (SERD).
The Company's OP-1250 is an oral small molecule clinical-stage product candidate for the treatment of endocrine-driven cancers. OP-1250, both as a monotherapy and in combination with inhibitors of cyclin-dependent kinase four and six (CDK4/6) demonstrated robust tumor shrinkage in several xenograft models, including ESR1 and PIK3CA mutations and central nervous system (CNS), metastasis.
It is in the Phase I/ II clinical trial, and in Phase Ib/ II combination with palbociclib, in patients with metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 560.1K |
Three Month Average Volume | 18.8M |
High Low | |
Fifty-Two Week High | 17.7911 USD |
Fifty-Two Week Low | 8.51 USD |
Fifty-Two Week High Date | 08 Nov 2023 |
Fifty-Two Week Low Date | 24 May 2024 |
Price and Volume | |
Current Price | 11.8 USD |
Beta | 2 |
Relative Price Change | |
Four Week Relative Price Change | -20.90% |
Thirteen Week Relative Price Change | 13.90% |
Twenty-Six Week Relative Price Change | -27.49% |
Fifty-Two Week Relative Price Change | -7.22% |
Year-to-Date Relative Price Change | -28.98% |
Price Change | |
One Day Price Change | 2.16% |
Thirteen Week Price Change | 21.90% |
Twenty-Six Week Price Change | -20.27% |
Five Day Price Change | -1.26% |
Fifty-Two Week Price Change | 16.26% |
Year-to-Date Price Change | -15.89% |
Month-to-Date Price Change | -26.98% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 4.61688 USD |
Book Value Per Share (Most Recent Quarter) | 3.96733 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 4.61688 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 3.96733 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -2.28998 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0 USD |
Revenue Per Share (Trailing Twelve Months) | 0 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -2.13616 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -2.06201 USD |
Normalized (Last Fiscal Year) | -2.13616 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -2.13616 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -2.06201 USD |
Including Extraordinary Items (Last Fiscal Year) | -2.13616 USD |
Including Extraordinary Items (Trailing Twelve Months) | -2.06201 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 4.76075 USD |
Cash Per Share (Most Recent Quarter) | 4.17588 USD |
Cash Flow Per Share (Last Fiscal Year) | -2.12783 USD |
Cash Flow Per Share (Trailing Twelve Months) | -2.06335 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -1.74542 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -100,000 |
Cash Flow Revenue (Trailing Twelve Months) | -100,000 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -99,999.99% |
Pretax Margin (Last Fiscal Year) | -99,999.99% |
Pretax Margin (5 Year) | -99,999.99% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -99,999.99% |
Operating Margin (Trailing Twelve Months) | -99,999.99% |
Operating Margin (5 Year) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -99,999.99% |
Net Profit Margin (Trailing Twelve Months) | -99,999.99% |
Net Profit Margin (5 Year) | -99,999.99% |
Growth | |
---|---|
Book Value | |
Book Value Per Share (5 Year) | 125.21% |
Tangible Book Value (5 Year) | 141.83% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -99,999.99% |
Revenue Growth (3 Year) | -99,999.99% |
Revenue Change (Trailing Twelve Months) | -99,999.99% |
Revenue Per Share Growth | -99,999.99% |
Revenue Growth (5 Year) | -99,999.99% |
Capital Spending Debt | |
Capital Spending (5 Year) | -99,999.99% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | -9.39% |
EPS Change (Trailing Twelve Months) | 14.56% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
---|---|
Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 3 |
Price to Tangible Book (Most Recent Quarter) | 3 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -239,104,000 |
Net Debt (Last Fiscal Year) | -261,807,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | -100,000 |
Price to Sales (Trailing Twelve Months) | -100,000 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 3 |
Price to Book (Most Recent Quarter) | 3 |
Financial Strength | |
---|---|
Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 0 |
Long Term Debt to Equity (Most Recent Quarter) | 0 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 12 |
Current Ratio (Most Recent Quarter) | 9 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -83,727,000 |
Free Cash Flow (Trailing Twelve Months) | -92,430,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -100,000 |
Net Interest Coverage (Trailing Twelve Months) | -100,000 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 0 |
Total Debt to Equity (Most Recent Quarter) | 0 |
Management Effectiveness | |
---|---|
Return on Assets | |
Return on Assets (Last Fiscal Year) | -39.24% |
Return on Assets (Trailing Twelve Months) | -50.73% |
Return on Assets (5 Year) | -30.06% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -42.82% |
Return on Equity (Trailing Twelve Months) | -56.40% |
Return on Equity (5 Year) | -32.23% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -42.54% |
Return on Investment (Trailing Twelve Months) | -56.10% |
Return on Investment (5 Year) | -31.40% |