Avalo Therapeutics, Inc. is a clinical-stage biotechnology company focused on the treatment of immune dysregulation. The Company's lead asset is AVTX-009, an anti-IL-1β mAb, targeting inflammatory diseases. Its pipeline also includes quisovalimab (anti-LIGHT mAb) and AVTX-008 (BTLA agonist fusion protein).
AVTX-009 is a humanized monoclonal antibody (IgG4) that binds to interleukin-1β (IL-1β) with high affinity and neutralizes its activity. IL- 1β is a central driver in the inflammatory process. Quisovalimab is a fully human monoclonal antibody (mAb), directed against human LIGHT (Lymphotoxin-like, exhibits Inducible expression, and competes with Herpes Virus Glycoprotein D for Herpesvirus Entry Mediator (HVEM), a receptor expressed by T lymphocytes).
AVTX-008 is a fully human B and T Lymphocyte Attenuator (BTLA) agonist fusion protein. AVTX-008 is differentiated by having specific binding to BTLA, with no binding to LIGHT or CD160..
| Price and Volume | |
|---|---|
| Volume | |
| Ten Day Average Volume | 49.0K | 
| Three Month Average Volume | 377.9K | 
| High Low | |
| Fifty-Two Week High | 71.04 USD | 
| Fifty-Two Week Low | 3.9501 USD | 
| Fifty-Two Week High Date | 14 Sep 2023 | 
| Fifty-Two Week Low Date | 17 Jan 2024 | 
| Price and Volume | |
| Current Price | 7 USD | 
| Beta | 1 | 
| Relative Price Change | |
| Four Week Relative Price Change | -38.65% | 
| Thirteen Week Relative Price Change | -44.03% | 
| Twenty-Six Week Relative Price Change | 44.03% | 
| Fifty-Two Week Relative Price Change | -76.72% | 
| Year-to-Date Relative Price Change | -35.04% | 
| Price Change | |
| One Day Price Change | -22.65% | 
| Thirteen Week Price Change | -40.09% | 
| Twenty-Six Week Price Change | 58.37% | 
| Five Day Price Change | -23.91% | 
| Fifty-Two Week Price Change | -70.83% | 
| Year-to-Date Price Change | -23.08% | 
| Month-to-Date Price Change | -38.49% | 
| Per Share Data | |
|---|---|
| Book Value | |
| Book Value Per Share (Last Fiscal Year) | 9.11007 USD | 
| Book Value Per Share (Most Recent Quarter) | -2.08001 USD | 
| Tangible Book Value Per Share (Last Fiscal Year) | -3.98877 USD | 
| Tangible Book Value Per Share (Most Recent Quarter) | -12.23541 USD | 
| EBITD | |
| EBITD Per Share (Trailing Twelve Months) | -9.14371 USD | 
| Revenue | |
| Revenue Per Share (Last Fiscal Year) | 6.92759 USD | 
| Revenue Per Share (Trailing Twelve Months) | 0.33465 USD | 
| Dividend | |
| Dividend Per Share (Last Fiscal Year) | -99999.99 USD | 
| Dividend Per Share (Trailing Twelve Months) | 0 USD | 
| Dividend Per Share (5 Year) | -99999.99 USD | 
| Earnings Per Share | |
| Excluding Extraordinary Items (Last Fiscal Year) | -113.5792 USD | 
| Excluding Extraordinary Items (Trailing Twelve Months) | -63.8218 USD | 
| Normalized (Last Fiscal Year) | -104.4351 USD | 
| Basic Excluding Extraordinary Items (Last Fiscal Year) | -113.5792 USD | 
| Basic Excluding Extraordinary Items (Trailing Twelve Months) | -60.1804 USD | 
| Including Extraordinary Items (Last Fiscal Year) | -113.5792 USD | 
| Including Extraordinary Items (Trailing Twelve Months) | -63.8218 USD | 
| Cash | |
| Cash Per Share (Last Fiscal Year) | 9.24852 USD | 
| Cash Per Share (Most Recent Quarter) | 90.34261 USD | 
| Cash Flow Per Share (Last Fiscal Year) | -113.009 USD | 
| Cash Flow Per Share (Trailing Twelve Months) | -14.95836 USD | 
| Free Cash Flow Per Share (Trailing Twelve Months) | -13.30585 USD | 
| Margins | |
|---|---|
| Cash Flow Revenue | |
| Cash Flow Revenue (5 Year) | -486 | 
| Cash Flow Revenue (Trailing Twelve Months) | -3,976 | 
| Pretax Margin | |
| Pretax Margin (Trailing Twelve Months) | -4,486.99% | 
| Pretax Margin (Last Fiscal Year) | -1,638.77% | 
| Pretax Margin (5 Year) | -620.45% | 
| Gross Margin | |
| Gross Margin (Last Fiscal Year) | 33.26% | 
| Gross Margin (Trailing Twelve Months) | 64.19% | 
| Gross Margin (5 Year) | 84.69% | 
| Operating Margin | |
| Operating Margin (Last Fiscal Year) | -1,421.57% | 
| Operating Margin (Trailing Twelve Months) | -6,660.35% | 
| Operating Margin (5 Year) | -607.66% | 
| Net Profit Margin | |
| Net Profit Margin (Last Fiscal Year) | -1,639.50% | 
| Net Profit Margin (Trailing Twelve Months) | -4,488.60% | 
| Net Profit Margin (5 Year) | -613.58% | 
| Growth | |
|---|---|
| Book Value | |
| Book Value Per Share (5 Year) | -63.84% | 
| Tangible Book Value (5 Year) | -99,999.99% | 
| Free Operating Cash Flow | |
| Free Operating Cash Flow (5 Year) | -99,999.99% | 
| Revenue | |
| Revenue Change MRQ vs 1 Year Ago | -100.00% | 
| Revenue Growth (3 Year) | -22.83% | 
| Revenue Change (Trailing Twelve Months) | -95.24% | 
| Revenue Per Share Growth | -58.78% | 
| Revenue Growth (5 Year) | -34.02% | 
| Capital Spending Debt | |
| Capital Spending (5 Year) | -22.48% | 
| Total Debt (5 Year) | -99,999.99% | 
| Dividends | |
| Dividend Growth (3 Year) | -99,999.99% | 
| Earnings Per Share | |
| EPS Change MRQ vs 1 Year Ago | 100.40% | 
| EPS Change (Trailing Twelve Months) | 87.56% | 
| EPS Growth (3 Year) | -99,999.99% | 
| EPS Growth (5 Year) | -99,999.99% | 
| EBITDA | |
| EBITDA (5 Year) | -99,999.99% | 
| EBITDA (5 Year Interim) | -99,999.99% | 
| Net Profit Margin | |
| Net Profit Margin Growth (5 Year) | -99,999.99% | 
| Valuation | |
|---|---|
| Total Price to Book | |
| Price to Tangible Book (Last Fiscal Year) | -100,000 | 
| Price to Tangible Book (Most Recent Quarter) | -100,000 | 
| Price to Free Cash Flow | |
| Price to Free Cash Per Share (Last Fiscal Year) | -100,000 | 
| Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 | 
| Net Debt | |
| Net Debt (Most Recent Quarter) | -93,426,000 | 
| Net Debt (Last Fiscal Year) | -7,415,000 | 
| Price to Sales | |
| Price to Sales (Last Fiscal Year) | 4 | 
| Price to Sales (Trailing Twelve Months) | 9 | 
| Price to Earnings | |
| PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 | 
| PE Normalized (Last Fiscal Year) | -100,000 | 
| PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 | 
| PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 | 
| PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 | 
| PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 | 
| Dividends | |
| Dividend Yield (5 Year) | -99,999.99% | 
| Dividend Yield | -99,999.99% | 
| Current Dividend Yield | 0.00% | 
| Price to Book | |
| Price to Book (Last Fiscal Year) | 1 | 
| Price to Book (Most Recent Quarter) | -100,000 | 
| Financial Strength | |
|---|---|
| Debt to Equity | |
| Long Term Debt to Equity (Last Fiscal Year) | 0 | 
| Long Term Debt to Equity (Most Recent Quarter) | -100,000 | 
| Payout Ratio | |
| Payout Ratio (Last Fiscal Year) | -99,999.99% | 
| Payout Ratio (Trailing Twelve Months) | -99,999.99% | 
| Quick Ratio | |
| Quick Ratio (Last Fiscal Year) | 2 | 
| Quick Ratio (Most Recent Quarter) | -100,000 | 
| Enterprise Value | |
| Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 | 
| Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 | 
| Current Ratio | |
| Current Ratio (Last Fiscal Year) | 2 | 
| Current Ratio (Most Recent Quarter) | 1 | 
| Free Cash Flow | |
| Free Cash Flow (Last Fiscal Year) | -30,838,000 | 
| Free Cash Flow (Trailing Twelve Months) | -32,087,000 | 
| Net Interest Coverage | |
| Net Interest Coverage (Last Fiscal Year) | -6 | 
| Net Interest Coverage (Trailing Twelve Months) | -100,000 | 
| Total Debt to Equity | |
| Total Debt to Equity (Last Fiscal Year) | 0 | 
| Total Debt to Equity (Most Recent Quarter) | -100,000 | 
| Management Effectiveness | |
|---|---|
| Return on Assets | |
| Return on Assets (Last Fiscal Year) | -116.06% | 
| Return on Assets (Trailing Twelve Months) | -54.66% | 
| Return on Assets (5 Year) | -99.64% | 
| Return on Equity | |
| Return on Equity (Last Fiscal Year) | -99,999.99% | 
| Return on Equity (Trailing Twelve Months) | -99,999.99% | 
| Return on Equity (5 Year) | -331.65% | 
| Return on Investment | |
| Return on Investment (Last Fiscal Year) | -228.35% | 
| Return on Investment (Trailing Twelve Months) | -529.15% | 
| Return on Investment (5 Year) | -154.42% |