Avalo Therapeutics, Inc. is a clinical-stage biotechnology company focused on the treatment of immune dysregulation. The Company's lead asset is AVTX-009, an anti-IL-1β mAb, targeting inflammatory diseases. Its pipeline also includes quisovalimab (anti-LIGHT mAb) and AVTX-008 (BTLA agonist fusion protein).
AVTX-009 is a humanized monoclonal antibody (IgG4) that binds to interleukin-1β (IL-1β) with high affinity and neutralizes its activity. IL- 1β is a central driver in the inflammatory process. Quisovalimab is a fully human monoclonal antibody (mAb), directed against human LIGHT (Lymphotoxin-like, exhibits Inducible expression, and competes with Herpes Virus Glycoprotein D for Herpesvirus Entry Mediator (HVEM), a receptor expressed by T lymphocytes).
AVTX-008 is a fully human B and T Lymphocyte Attenuator (BTLA) agonist fusion protein. AVTX-008 is differentiated by having specific binding to BTLA, with no binding to LIGHT or CD160..
Price and Volume | |
---|---|
Volume | |
Ten Day Average Volume | 49.0K |
Three Month Average Volume | 377.9K |
High Low | |
Fifty-Two Week High | 71.04 USD |
Fifty-Two Week Low | 3.9501 USD |
Fifty-Two Week High Date | 14 Sep 2023 |
Fifty-Two Week Low Date | 17 Jan 2024 |
Price and Volume | |
Current Price | 7 USD |
Beta | 1 |
Relative Price Change | |
Four Week Relative Price Change | -38.65% |
Thirteen Week Relative Price Change | -44.03% |
Twenty-Six Week Relative Price Change | 44.03% |
Fifty-Two Week Relative Price Change | -76.72% |
Year-to-Date Relative Price Change | -35.04% |
Price Change | |
One Day Price Change | -22.65% |
Thirteen Week Price Change | -40.09% |
Twenty-Six Week Price Change | 58.37% |
Five Day Price Change | -23.91% |
Fifty-Two Week Price Change | -70.83% |
Year-to-Date Price Change | -23.08% |
Month-to-Date Price Change | -38.49% |
Per Share Data | |
---|---|
Book Value | |
Book Value Per Share (Last Fiscal Year) | 9.11007 USD |
Book Value Per Share (Most Recent Quarter) | -2.08001 USD |
Tangible Book Value Per Share (Last Fiscal Year) | -3.98877 USD |
Tangible Book Value Per Share (Most Recent Quarter) | -12.23541 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -9.14371 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 6.92759 USD |
Revenue Per Share (Trailing Twelve Months) | 0.33465 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | -113.5792 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -63.8218 USD |
Normalized (Last Fiscal Year) | -104.4351 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | -113.5792 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -60.1804 USD |
Including Extraordinary Items (Last Fiscal Year) | -113.5792 USD |
Including Extraordinary Items (Trailing Twelve Months) | -63.8218 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 9.24852 USD |
Cash Per Share (Most Recent Quarter) | 90.34261 USD |
Cash Flow Per Share (Last Fiscal Year) | -113.009 USD |
Cash Flow Per Share (Trailing Twelve Months) | -14.95836 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -13.30585 USD |
Margins | |
---|---|
Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -486 |
Cash Flow Revenue (Trailing Twelve Months) | -3,976 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -4,486.99% |
Pretax Margin (Last Fiscal Year) | -1,638.77% |
Pretax Margin (5 Year) | -620.45% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | 33.26% |
Gross Margin (Trailing Twelve Months) | 64.19% |
Gross Margin (5 Year) | 84.69% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -1,421.57% |
Operating Margin (Trailing Twelve Months) | -6,660.35% |
Operating Margin (5 Year) | -607.66% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -1,639.50% |
Net Profit Margin (Trailing Twelve Months) | -4,488.60% |
Net Profit Margin (5 Year) | -613.58% |
Growth | |
---|---|
Book Value | |
Book Value Per Share (5 Year) | -63.84% |
Tangible Book Value (5 Year) | -99,999.99% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -100.00% |
Revenue Growth (3 Year) | -22.83% |
Revenue Change (Trailing Twelve Months) | -95.24% |
Revenue Per Share Growth | -58.78% |
Revenue Growth (5 Year) | -34.02% |
Capital Spending Debt | |
Capital Spending (5 Year) | -22.48% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | 100.40% |
EPS Change (Trailing Twelve Months) | 87.56% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
---|---|
Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | -100,000 |
Price to Tangible Book (Most Recent Quarter) | -100,000 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -93,426,000 |
Net Debt (Last Fiscal Year) | -7,415,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | 4 |
Price to Sales (Trailing Twelve Months) | 9 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 1 |
Price to Book (Most Recent Quarter) | -100,000 |
Financial Strength | |
---|---|
Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 0 |
Long Term Debt to Equity (Most Recent Quarter) | -100,000 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | -99,999.99% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | 2 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 2 |
Current Ratio (Most Recent Quarter) | 1 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -30,838,000 |
Free Cash Flow (Trailing Twelve Months) | -32,087,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -6 |
Net Interest Coverage (Trailing Twelve Months) | -100,000 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 0 |
Total Debt to Equity (Most Recent Quarter) | -100,000 |
Management Effectiveness | |
---|---|
Return on Assets | |
Return on Assets (Last Fiscal Year) | -116.06% |
Return on Assets (Trailing Twelve Months) | -54.66% |
Return on Assets (5 Year) | -99.64% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | -99,999.99% |
Return on Equity (Trailing Twelve Months) | -99,999.99% |
Return on Equity (5 Year) | -331.65% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | -228.35% |
Return on Investment (Trailing Twelve Months) | -529.15% |
Return on Investment (5 Year) | -154.42% |