Iovance Biotherapeutics
Iovance Biotherapeutics
IOVA
NASDAQ
11.66
USD
82.19%
About
Iovance Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company develops and delivers tumor infiltrating lymphocyte (TIL), therapies for patients with solid tumor cancers. Its lead product candidate, Amtagvi (lifileucel), is a tumor-derived autologous T cell immunotherapy indicated for the treatment of adult patients with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody, and if BRAF V600 mutation positive, a BRAF inhibitor with or without a MEK inhibitor.
The Company also marketing Proleukin (aldesleukin), aninterleukin-2, or IL-2, product used in the Amtagvi treatment regimen. Its development pipeline includes multicenter trials of TIL cell therapies in additional treatment settings for solid tumor cancers. Amtagvi and Proleukin are part of a treatment regimen that also includes lymphodepletion.
The Company is also developing next generation therapies using TIL, such as genetically modified TIL cell therapy..
Financials Amount (in millions)
Income statement
Balance sheet
Cash flow
Ratios
| Price and Volume | |
|---|---|
| Volume | |
| Ten Day Average Volume | 5.8M |
| Three Month Average Volume | 153.4M |
| High Low | |
| Fifty-Two Week High | 18.33 USD |
| Fifty-Two Week Low | 3.21 USD |
| Fifty-Two Week High Date | 28 Feb 2024 |
| Fifty-Two Week Low Date | 19 Oct 2023 |
| Price and Volume | |
| Current Price | 11.66 USD |
| Beta | 1 |
| Relative Price Change | |
| Four Week Relative Price Change | 41.68% |
| Thirteen Week Relative Price Change | 22.68% |
| Twenty-Six Week Relative Price Change | -36.84% |
| Fifty-Two Week Relative Price Change | 54.06% |
| Year-to-Date Relative Price Change | 21.11% |
| Price Change | |
| One Day Price Change | 2.46% |
| Thirteen Week Price Change | 31.31% |
| Twenty-Six Week Price Change | -30.55% |
| Five Day Price Change | -1.77% |
| Fifty-Two Week Price Change | 93.05% |
| Year-to-Date Price Change | 43.42% |
| Month-to-Date Price Change | 33.56% |
| Per Share Data | |
|---|---|
| Book Value | |
| Book Value Per Share (Last Fiscal Year) | 2.28243 USD |
| Book Value Per Share (Most Recent Quarter) | 2.58501 USD |
| Tangible Book Value Per Share (Last Fiscal Year) | 1.38737 USD |
| Tangible Book Value Per Share (Most Recent Quarter) | 1.59176 USD |
| EBITD | |
| EBITD Per Share (Trailing Twelve Months) | -1.6307 USD |
| Revenue | |
| Revenue Per Share (Last Fiscal Year) | 0.00506 USD |
| Revenue Per Share (Trailing Twelve Months) | 0.12449 USD |
| Dividend | |
| Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
| Dividend Per Share (Trailing Twelve Months) | 0 USD |
| Dividend Per Share (5 Year) | -99999.99 USD |
| Earnings Per Share | |
| Excluding Extraordinary Items (Last Fiscal Year) | -1.88847 USD |
| Excluding Extraordinary Items (Trailing Twelve Months) | -1.68236 USD |
| Normalized (Last Fiscal Year) | -1.88847 USD |
| Basic Excluding Extraordinary Items (Last Fiscal Year) | -1.88847 USD |
| Basic Excluding Extraordinary Items (Trailing Twelve Months) | -1.68236 USD |
| Including Extraordinary Items (Last Fiscal Year) | -1.88847 USD |
| Including Extraordinary Items (Trailing Twelve Months) | -1.68236 USD |
| Cash | |
| Cash Per Share (Last Fiscal Year) | 1.09265 USD |
| Cash Per Share (Most Recent Quarter) | 1.3876 USD |
| Cash Flow Per Share (Last Fiscal Year) | -1.79724 USD |
| Cash Flow Per Share (Trailing Twelve Months) | -1.55838 USD |
| Free Cash Flow Per Share (Trailing Twelve Months) | -1.52124 USD |
| Margins | |
|---|---|
| Cash Flow Revenue | |
| Cash Flow Revenue (5 Year) | -116,109 |
| Cash Flow Revenue (Trailing Twelve Months) | -1,222 |
| Pretax Margin | |
| Pretax Margin (Trailing Twelve Months) | -1,361.17% |
| Pretax Margin (Last Fiscal Year) | -37,638.02% |
| Pretax Margin (5 Year) | -138,166.40% |
| Gross Margin | |
| Gross Margin (Last Fiscal Year) | -804.54% |
| Gross Margin (Trailing Twelve Months) | -37.43% |
| Gross Margin (5 Year) | -99,999.99% |
| Operating Margin | |
| Operating Margin (Last Fiscal Year) | -38,734.99% |
| Operating Margin (Trailing Twelve Months) | -1,401.36% |
| Operating Margin (5 Year) | -140,534.00% |
| Net Profit Margin | |
| Net Profit Margin (Last Fiscal Year) | -37,345.42% |
| Net Profit Margin (Trailing Twelve Months) | -1,343.27% |
| Net Profit Margin (5 Year) | -137,873.80% |
| Growth | |
|---|---|
| Book Value | |
| Book Value Per Share (5 Year) | -9.58% |
| Tangible Book Value (5 Year) | -5.28% |
| Free Operating Cash Flow | |
| Free Operating Cash Flow (5 Year) | -99,999.99% |
| Revenue | |
| Revenue Change MRQ vs 1 Year Ago | 12,969.75% |
| Revenue Growth (3 Year) | -99,999.99% |
| Revenue Change (Trailing Twelve Months) | 13,669.75% |
| Revenue Per Share Growth | -99,999.99% |
| Revenue Growth (5 Year) | -99,999.99% |
| Capital Spending Debt | |
| Capital Spending (5 Year) | 79.44% |
| Total Debt (5 Year) | -99,999.99% |
| Dividends | |
| Dividend Growth (3 Year) | -99,999.99% |
| Earnings Per Share | |
| EPS Change MRQ vs 1 Year Ago | 28.16% |
| EPS Change (Trailing Twelve Months) | 25.14% |
| EPS Growth (3 Year) | -99,999.99% |
| EPS Growth (5 Year) | -99,999.99% |
| EBITDA | |
| EBITDA (5 Year) | -99,999.99% |
| EBITDA (5 Year Interim) | -99,999.99% |
| Net Profit Margin | |
| Net Profit Margin Growth (5 Year) | -99,999.99% |
| Valuation | |
|---|---|
| Total Price to Book | |
| Price to Tangible Book (Last Fiscal Year) | 10 |
| Price to Tangible Book (Most Recent Quarter) | 7 |
| Price to Free Cash Flow | |
| Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
| Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
| Net Debt | |
| Net Debt (Most Recent Quarter) | -411,542,000 |
| Net Debt (Last Fiscal Year) | -278,867,000 |
| Price to Sales | |
| Price to Sales (Last Fiscal Year) | 3.0K |
| Price to Sales (Trailing Twelve Months) | 108 |
| Price to Earnings | |
| PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
| PE Normalized (Last Fiscal Year) | -100,000 |
| PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
| PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
| PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
| PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
| Dividends | |
| Dividend Yield (5 Year) | -99,999.99% |
| Dividend Yield | -99,999.99% |
| Current Dividend Yield | 0.00% |
| Price to Book | |
| Price to Book (Last Fiscal Year) | 5 |
| Price to Book (Most Recent Quarter) | 5 |
| Financial Strength | |
|---|---|
| Debt to Equity | |
| Long Term Debt to Equity (Last Fiscal Year) | 0 |
| Long Term Debt to Equity (Most Recent Quarter) | 0 |
| Payout Ratio | |
| Payout Ratio (Last Fiscal Year) | -99,999.99% |
| Payout Ratio (Trailing Twelve Months) | -99,999.99% |
| Quick Ratio | |
| Quick Ratio (Last Fiscal Year) | 3 |
| Quick Ratio (Most Recent Quarter) | 5 |
| Enterprise Value | |
| Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
| Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
| Current Ratio | |
| Current Ratio (Last Fiscal Year) | 3 |
| Current Ratio (Most Recent Quarter) | 5 |
| Free Cash Flow | |
| Free Cash Flow (Last Fiscal Year) | -384,110,000 |
| Free Cash Flow (Trailing Twelve Months) | -400,480,000 |
| Net Interest Coverage | |
| Net Interest Coverage (Last Fiscal Year) | -100,000 |
| Net Interest Coverage (Trailing Twelve Months) | -100,000 |
| Total Debt to Equity | |
| Total Debt to Equity (Last Fiscal Year) | 0 |
| Total Debt to Equity (Most Recent Quarter) | 0 |
| Management Effectiveness | |
|---|---|
| Return on Assets | |
| Return on Assets (Last Fiscal Year) | -61.49% |
| Return on Assets (Trailing Twelve Months) | -51.14% |
| Return on Assets (5 Year) | -51.47% |
| Return on Equity | |
| Return on Equity (Last Fiscal Year) | -81.91% |
| Return on Equity (Trailing Twelve Months) | -65.36% |
| Return on Equity (5 Year) | -63.00% |
| Return on Investment | |
| Return on Investment (Last Fiscal Year) | -71.47% |
| Return on Investment (Trailing Twelve Months) | -57.20% |
| Return on Investment (5 Year) | -57.56% |