AVROBIO, Inc. is a gene therapy company. The Company is focused on developing potentially curative hematopoietic stem cells (HSC) gene therapies to treat patients with rare diseases following a single dose treatment regimen. The gene therapies that the Company is engaged in developing employ HSCs that are harvested from the patient and then modified with a lentiviral vector to insert the equivalent of a functional copy of the gene that is mutated in the target disease.
The Company's development focus has been on a group of rare genetic diseases referred to as lysosomal disorders, primarily managed with enzyme replacement therapies (ERTs). Its pipeline is comprised of three HSC gene therapy programs, which include AVR-RD-02 for the treatment of Gaucher disease type 1 and type 3; AVR-RD-03 for the treatment of Pompe disease, and AVR-RD-01 for the treatment of Fabry disease..
Price and Volume | |
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Volume | |
Ten Day Average Volume | 23.2K |
Three Month Average Volume | 550.3K |
High Low | |
Fifty-Two Week High | 19.8 USD |
Fifty-Two Week Low | 12.12 USD |
Fifty-Two Week High Date | 06 Sep 2023 |
Fifty-Two Week Low Date | 30 Jan 2024 |
Price and Volume | |
Current Price | 19.2 USD |
Beta | 1 |
Relative Price Change | |
Four Week Relative Price Change | 5.97% |
Thirteen Week Relative Price Change | 1.01% |
Twenty-Six Week Relative Price Change | 9.41% |
Fifty-Two Week Relative Price Change | -16.00% |
Year-to-Date Relative Price Change | -0.65% |
Price Change | |
One Day Price Change | 1.05% |
Thirteen Week Price Change | 8.11% |
Twenty-Six Week Price Change | 20.30% |
Five Day Price Change | 5.49% |
Fifty-Two Week Price Change | 5.26% |
Year-to-Date Price Change | 17.65% |
Month-to-Date Price Change | 7.14% |
Per Share Data | |
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Book Value | |
Book Value Per Share (Last Fiscal Year) | 25.46049 USD |
Book Value Per Share (Most Recent Quarter) | 11.29112 USD |
Tangible Book Value Per Share (Last Fiscal Year) | 25.46049 USD |
Tangible Book Value Per Share (Most Recent Quarter) | 11.29112 USD |
EBITD | |
EBITD Per Share (Trailing Twelve Months) | -16.79149 USD |
Revenue | |
Revenue Per Share (Last Fiscal Year) | 0 USD |
Revenue Per Share (Trailing Twelve Months) | 0 USD |
Dividend | |
Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
Dividend Per Share (Trailing Twelve Months) | 0 USD |
Dividend Per Share (5 Year) | -99999.99 USD |
Earnings Per Share | |
Excluding Extraordinary Items (Last Fiscal Year) | 3.27329 USD |
Excluding Extraordinary Items (Trailing Twelve Months) | -18.52225 USD |
Normalized (Last Fiscal Year) | -10.8888 USD |
Basic Excluding Extraordinary Items (Last Fiscal Year) | 3.29109 USD |
Basic Excluding Extraordinary Items (Trailing Twelve Months) | -18.52225 USD |
Including Extraordinary Items (Last Fiscal Year) | 3.27329 USD |
Including Extraordinary Items (Trailing Twelve Months) | -18.52225 USD |
Cash | |
Cash Per Share (Last Fiscal Year) | 26.34224 USD |
Cash Per Share (Most Recent Quarter) | 12.56414 USD |
Cash Flow Per Share (Last Fiscal Year) | 3.43942 USD |
Cash Flow Per Share (Trailing Twelve Months) | -17.76863 USD |
Free Cash Flow Per Share (Trailing Twelve Months) | -15.8072 USD |
Margins | |
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Cash Flow Revenue | |
Cash Flow Revenue (5 Year) | -100,000 |
Cash Flow Revenue (Trailing Twelve Months) | -100,000 |
Pretax Margin | |
Pretax Margin (Trailing Twelve Months) | -99,999.99% |
Pretax Margin (Last Fiscal Year) | -99,999.99% |
Pretax Margin (5 Year) | -99,999.99% |
Gross Margin | |
Gross Margin (Last Fiscal Year) | -99,999.99% |
Gross Margin (Trailing Twelve Months) | -99,999.99% |
Gross Margin (5 Year) | -99,999.99% |
Operating Margin | |
Operating Margin (Last Fiscal Year) | -99,999.99% |
Operating Margin (Trailing Twelve Months) | -99,999.99% |
Operating Margin (5 Year) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin (Last Fiscal Year) | -99,999.99% |
Net Profit Margin (Trailing Twelve Months) | -99,999.99% |
Net Profit Margin (5 Year) | -99,999.99% |
Growth | |
---|---|
Book Value | |
Book Value Per Share (5 Year) | -16.19% |
Tangible Book Value (5 Year) | -4.96% |
Free Operating Cash Flow | |
Free Operating Cash Flow (5 Year) | -99,999.99% |
Revenue | |
Revenue Change MRQ vs 1 Year Ago | -99,999.99% |
Revenue Growth (3 Year) | -99,999.99% |
Revenue Change (Trailing Twelve Months) | -99,999.99% |
Revenue Per Share Growth | -99,999.99% |
Revenue Growth (5 Year) | -99,999.99% |
Capital Spending Debt | |
Capital Spending (5 Year) | -66.27% |
Total Debt (5 Year) | -99,999.99% |
Dividends | |
Dividend Growth (3 Year) | -99,999.99% |
Earnings Per Share | |
EPS Change MRQ vs 1 Year Ago | -123.73% |
EPS Change (Trailing Twelve Months) | -1,007.84% |
EPS Growth (3 Year) | -99,999.99% |
EPS Growth (5 Year) | -99,999.99% |
EBITDA | |
EBITDA (5 Year) | -99,999.99% |
EBITDA (5 Year Interim) | -99,999.99% |
Net Profit Margin | |
Net Profit Margin Growth (5 Year) | -99,999.99% |
Valuation | |
---|---|
Total Price to Book | |
Price to Tangible Book (Last Fiscal Year) | 3 |
Price to Tangible Book (Most Recent Quarter) | 2 |
Price to Free Cash Flow | |
Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
Net Debt | |
Net Debt (Most Recent Quarter) | -184,013,000 |
Net Debt (Last Fiscal Year) | -98,020,000 |
Price to Sales | |
Price to Sales (Last Fiscal Year) | -100,000 |
Price to Sales (Trailing Twelve Months) | -100,000 |
Price to Earnings | |
PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
PE Normalized (Last Fiscal Year) | -100,000 |
PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
PE Excluding Extraordinary Items High (Trailing Twelve Months) | 5 |
PE Excluding Extraordinary Items Low (Trailing Twelve Months) | 4 |
PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
Dividends | |
Dividend Yield (5 Year) | -99,999.99% |
Dividend Yield | -99,999.99% |
Current Dividend Yield | 0.00% |
Price to Book | |
Price to Book (Last Fiscal Year) | 1 |
Price to Book (Most Recent Quarter) | 2 |
Financial Strength | |
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Debt to Equity | |
Long Term Debt to Equity (Last Fiscal Year) | 0 |
Long Term Debt to Equity (Most Recent Quarter) | 0 |
Payout Ratio | |
Payout Ratio (Last Fiscal Year) | 0.00% |
Payout Ratio (Trailing Twelve Months) | -99,999.99% |
Quick Ratio | |
Quick Ratio (Last Fiscal Year) | -100,000 |
Quick Ratio (Most Recent Quarter) | -100,000 |
Enterprise Value | |
Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | 14 |
Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
Current Ratio | |
Current Ratio (Last Fiscal Year) | 16 |
Current Ratio (Most Recent Quarter) | 7 |
Free Cash Flow | |
Free Cash Flow (Last Fiscal Year) | -63,198,000 |
Free Cash Flow (Trailing Twelve Months) | -50,909,000 |
Net Interest Coverage | |
Net Interest Coverage (Last Fiscal Year) | -100,000 |
Net Interest Coverage (Trailing Twelve Months) | -129 |
Total Debt to Equity | |
Total Debt to Equity (Last Fiscal Year) | 0 |
Total Debt to Equity (Most Recent Quarter) | 1 |
Management Effectiveness | |
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Return on Assets | |
Return on Assets (Last Fiscal Year) | 11.86% |
Return on Assets (Trailing Twelve Months) | -35.55% |
Return on Assets (5 Year) | -45.22% |
Return on Equity | |
Return on Equity (Last Fiscal Year) | 14.29% |
Return on Equity (Trailing Twelve Months) | -40.40% |
Return on Equity (5 Year) | -51.10% |
Return on Investment | |
Return on Investment (Last Fiscal Year) | 13.10% |
Return on Investment (Trailing Twelve Months) | -40.16% |
Return on Investment (5 Year) | -49.14% |