Stoke Therapeutics
Stoke Therapeutics
STOK
NASDAQ
8.20
USD
0.00%
About
Stoke Therapeutics, Inc. is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with ribonucleic acid (RNA)-based medicines. The Company, through its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach, is engaged in developing antisense oligonucleotides (ASOs) to selectively restore protein levels.
Its first compound, STK-001, is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. TANGO aims to restore missing proteins by increasing or stoking protein output from healthy genes, thus compensating for the non-functioning copy of the gene. The Company is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder.
The Company’s initial focus is haploinsufficiency and diseases of the central nervous system and the eye..
Financials Amount (in millions)
Income statement
Balance sheet
Cash flow
Ratios
| Price and Volume | |
|---|---|
| Volume | |
| Ten Day Average Volume | 340.1K |
| Three Month Average Volume | 12.8M |
| High Low | |
| Fifty-Two Week High | 17.58 USD |
| Fifty-Two Week Low | 3.35 USD |
| Fifty-Two Week High Date | 13 Jun 2024 |
| Fifty-Two Week Low Date | 27 Oct 2023 |
| Price and Volume | |
| Current Price | 14.55 USD |
| Beta | 1 |
| Relative Price Change | |
| Four Week Relative Price Change | -4.75% |
| Thirteen Week Relative Price Change | -7.01% |
| Twenty-Six Week Relative Price Change | 73.43% |
| Fifty-Two Week Relative Price Change | 106.61% |
| Year-to-Date Relative Price Change | 133.59% |
| Price Change | |
| One Day Price Change | 4.68% |
| Thirteen Week Price Change | -0.48% |
| Twenty-Six Week Price Change | 90.69% |
| Five Day Price Change | 4.00% |
| Fifty-Two Week Price Change | 158.90% |
| Year-to-Date Price Change | 176.62% |
| Month-to-Date Price Change | -2.81% |
| Per Share Data | |
|---|---|
| Book Value | |
| Book Value Per Share (Last Fiscal Year) | 3.47498 USD |
| Book Value Per Share (Most Recent Quarter) | 4.64021 USD |
| Tangible Book Value Per Share (Last Fiscal Year) | 3.47498 USD |
| Tangible Book Value Per Share (Most Recent Quarter) | 4.64021 USD |
| EBITD | |
| EBITD Per Share (Trailing Twelve Months) | -2.34589 USD |
| Revenue | |
| Revenue Per Share (Last Fiscal Year) | 0.19957 USD |
| Revenue Per Share (Trailing Twelve Months) | 0.31701 USD |
| Dividend | |
| Dividend Per Share (Last Fiscal Year) | -99999.99 USD |
| Dividend Per Share (Trailing Twelve Months) | 0 USD |
| Dividend Per Share (5 Year) | -99999.99 USD |
| Earnings Per Share | |
| Excluding Extraordinary Items (Last Fiscal Year) | -2.3798 USD |
| Excluding Extraordinary Items (Trailing Twelve Months) | -2.18495 USD |
| Normalized (Last Fiscal Year) | -2.3798 USD |
| Basic Excluding Extraordinary Items (Last Fiscal Year) | -2.3798 USD |
| Basic Excluding Extraordinary Items (Trailing Twelve Months) | -2.18495 USD |
| Including Extraordinary Items (Last Fiscal Year) | -2.3798 USD |
| Including Extraordinary Items (Trailing Twelve Months) | -2.18495 USD |
| Cash | |
| Cash Per Share (Last Fiscal Year) | 4.38593 USD |
| Cash Per Share (Most Recent Quarter) | 5.39104 USD |
| Cash Flow Per Share (Last Fiscal Year) | -2.32368 USD |
| Cash Flow Per Share (Trailing Twelve Months) | -2.11656 USD |
| Free Cash Flow Per Share (Trailing Twelve Months) | -1.68627 USD |
| Margins | |
|---|---|
| Cash Flow Revenue | |
| Cash Flow Revenue (5 Year) | -1,239 |
| Cash Flow Revenue (Trailing Twelve Months) | -532 |
| Pretax Margin | |
| Pretax Margin (Trailing Twelve Months) | -683.31% |
| Pretax Margin (Last Fiscal Year) | -1,192.47% |
| Pretax Margin (5 Year) | -1,775.50% |
| Gross Margin | |
| Gross Margin (Last Fiscal Year) | -99,999.99% |
| Gross Margin (Trailing Twelve Months) | -99,999.99% |
| Gross Margin (5 Year) | -99,999.99% |
| Operating Margin | |
| Operating Margin (Last Fiscal Year) | -1,307.21% |
| Operating Margin (Trailing Twelve Months) | -755.65% |
| Operating Margin (5 Year) | -1,859.41% |
| Net Profit Margin | |
| Net Profit Margin (Last Fiscal Year) | -1,192.47% |
| Net Profit Margin (Trailing Twelve Months) | -683.31% |
| Net Profit Margin (5 Year) | -1,775.50% |
| Growth | |
|---|---|
| Book Value | |
| Book Value Per Share (5 Year) | 0.02% |
| Tangible Book Value (5 Year) | 8.72% |
| Free Operating Cash Flow | |
| Free Operating Cash Flow (5 Year) | -99,999.99% |
| Revenue | |
| Revenue Change MRQ vs 1 Year Ago | 294.72% |
| Revenue Growth (3 Year) | -99,999.99% |
| Revenue Change (Trailing Twelve Months) | 71.38% |
| Revenue Per Share Growth | -99,999.99% |
| Revenue Growth (5 Year) | -99,999.99% |
| Capital Spending Debt | |
| Capital Spending (5 Year) | 11.56% |
| Total Debt (5 Year) | -99,999.99% |
| Dividends | |
| Dividend Growth (3 Year) | -99,999.99% |
| Earnings Per Share | |
| EPS Change MRQ vs 1 Year Ago | 33.58% |
| EPS Change (Trailing Twelve Months) | 13.86% |
| EPS Growth (3 Year) | -99,999.99% |
| EPS Growth (5 Year) | -99,999.99% |
| EBITDA | |
| EBITDA (5 Year) | -99,999.99% |
| EBITDA (5 Year Interim) | -99,999.99% |
| Net Profit Margin | |
| Net Profit Margin Growth (5 Year) | -99,999.99% |
| Valuation | |
|---|---|
| Total Price to Book | |
| Price to Tangible Book (Last Fiscal Year) | 5 |
| Price to Tangible Book (Most Recent Quarter) | 3 |
| Price to Free Cash Flow | |
| Price to Free Cash Per Share (Last Fiscal Year) | -100,000 |
| Price to Free Cash Per Share (Trailing Twelve Months) | -100,000 |
| Net Debt | |
| Net Debt (Most Recent Quarter) | -281,982,000 |
| Net Debt (Last Fiscal Year) | -201,394,000 |
| Price to Sales | |
| Price to Sales (Last Fiscal Year) | 87 |
| Price to Sales (Trailing Twelve Months) | 51 |
| Price to Earnings | |
| PE Excluding Extraordinary Items (Last Fiscal Year) | -100,000 |
| PE Normalized (Last Fiscal Year) | -100,000 |
| PE Basic Excluding Extraordinary Items (Trailing Twelve Months) | -100,000 |
| PE Excluding Extraordinary Items High (Trailing Twelve Months) | -100,000 |
| PE Excluding Extraordinary Items Low (Trailing Twelve Months) | -100,000 |
| PE Including Extraordinary Items (Trailing Twelve Months) | -100,000 |
| Dividends | |
| Dividend Yield (5 Year) | -99,999.99% |
| Dividend Yield | -99,999.99% |
| Current Dividend Yield | 0.00% |
| Price to Book | |
| Price to Book (Last Fiscal Year) | 4 |
| Price to Book (Most Recent Quarter) | 3 |
| Financial Strength | |
|---|---|
| Debt to Equity | |
| Long Term Debt to Equity (Last Fiscal Year) | 0 |
| Long Term Debt to Equity (Most Recent Quarter) | 0 |
| Payout Ratio | |
| Payout Ratio (Last Fiscal Year) | -99,999.99% |
| Payout Ratio (Trailing Twelve Months) | -99,999.99% |
| Quick Ratio | |
| Quick Ratio (Last Fiscal Year) | -100,000 |
| Quick Ratio (Most Recent Quarter) | -100,000 |
| Enterprise Value | |
| Current Enterprise Value to Free Cash Flow (Last Fiscal Year) | -100,000 |
| Current Enterprise Value to Free Cash Flow (Trailing Twelve Months) | -100,000 |
| Current Ratio | |
| Current Ratio (Last Fiscal Year) | 7 |
| Current Ratio (Most Recent Quarter) | 7 |
| Free Cash Flow | |
| Free Cash Flow (Last Fiscal Year) | -82,683,000 |
| Free Cash Flow (Trailing Twelve Months) | -80,624,000 |
| Net Interest Coverage | |
| Net Interest Coverage (Last Fiscal Year) | -100,000 |
| Net Interest Coverage (Trailing Twelve Months) | -100,000 |
| Total Debt to Equity | |
| Total Debt to Equity (Last Fiscal Year) | 0 |
| Total Debt to Equity (Most Recent Quarter) | 0 |
| Management Effectiveness | |
|---|---|
| Return on Assets | |
| Return on Assets (Last Fiscal Year) | -43.23% |
| Return on Assets (Trailing Twelve Months) | -36.68% |
| Return on Assets (5 Year) | -31.62% |
| Return on Equity | |
| Return on Equity (Last Fiscal Year) | -60.80% |
| Return on Equity (Trailing Twelve Months) | -47.85% |
| Return on Equity (5 Year) | -35.98% |
| Return on Investment | |
| Return on Investment (Last Fiscal Year) | -49.60% |
| Return on Investment (Trailing Twelve Months) | -41.57% |
| Return on Investment (5 Year) | -33.92% |